Amnesia has been a plot device in cinema for decades, but when it's combined with comedy, it creates a unique blend of laughter and intrigue. This collection of 10 films showcases how memory loss can lead to comedic situations, misunderstandings, and heartwarming resolutions. Whether you're looking for a light-hearted escape or just want to see how characters navigate life with a blank slate, these films offer a delightful mix of humor and heart.

Overboard (1987)
Description: A wealthy woman loses her memory after falling off her yacht, and a carpenter she previously mistreated convinces her she's his wife. The ensuing comedy of errors is both heartwarming and hilarious.
Fact: The film was remade in 2018 with Anna Faris and Eugenio Derbez. Goldie Hawn, who played the lead in the original, was initially hesitant to take the role.


The Big Lebowski (1998)
Description: Jeff Bridges plays "The Dude," who gets mistaken for a millionaire with the same name, leading to a series of misadventures and memory lapses due to his laid-back lifestyle.
Fact: The film has developed a cult following, with annual festivals celebrating its humor and characters.


Dude, Where's My Car? (2000)
Description: Two friends wake up after a night of partying with no memory of where they parked their car, leading to a series of comedic events as they try to piece together the previous night.
Fact: The film features Ashton Kutcher and Seann William Scott, who both became known for their comedic roles following this movie.


50 First Dates (2004)
Description: Henry Roth falls for Lucy Whitmore, who has short-term memory loss, leading to a series of first dates every day. This film explores the comedic and romantic aspects of living with amnesia.
Fact: Adam Sandler and Drew Barrymore had such great chemistry that they starred together in two other romantic comedies. The film was shot in Hawaii, adding to its tropical charm.


The Lookout (2007)
Description: While not strictly a comedy, this film features Chris Pratt as a bank employee with amnesia who gets entangled in a heist. The comedic elements come from his attempts to navigate his new life.
Fact: Joseph Gordon-Levitt's performance was critically acclaimed, earning him several award nominations.


The Hangover (2009)
Description: Although not about amnesia, the film features a group of friends waking up with no memory of the previous night, leading to a comedic search for their missing friend.
Fact: The film was a surprise hit, spawning two sequels. It was inspired by the real-life experiences of the screenwriter.


The Vow (2012)
Description: After a car accident, Paige loses her memory of the last five years, including her marriage to Leo. This film blends romance with comedic elements as Leo tries to win back his wife's love.
Fact: The film is loosely based on a true story. Rachel McAdams and Channing Tatum had great chemistry, which was a key factor in the film's success.


The Longest Week (2014)
Description: A man with a fading memory of his past life tries to navigate his new reality, leading to humorous situations as he pretends to be someone he's not.
Fact: The film stars Olivia Wilde, who also served as an executive producer.


The Man Who Lost His Head (2007)
Description: A man wakes up to find his head is missing, leading to a surreal and comedic journey to find it, exploring themes of identity and memory.
Fact: This animated film is based on a children's book by Claire Huchet Bishop.


The Amnesia Clinic (2009)
Description: A group of people with amnesia meet at a clinic, leading to a series of comedic misunderstandings and a quest to remember their pasts.
Fact: This film was a low-budget production but gained a cult following for its unique take on the amnesia theme.
